Description
Antibody Name: | SYNC Antibody (PACO40418) |
Antibody SKU: | PACO40418 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Syncoilin protein (332-482AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Atypical type III intermediate filament (IF) protein that may play a supportive role in the efficient coupling of mechanical stress between the myofibril and fiber exterior. May facilitate lateral force transmission during skeletal muscle contraction. Does not form homofilaments nor heterofilaments with other IF proteins. |
Synonyms: | Syncoilin (Syncoilin intermediate filament 1) (Syncoilin-1), SYNC, SYNC1 |
UniProt Protein Function: | SYNC1: a member of the intermediate filament family which contains an N-terminal head domain, followed by a central coiled-coil region and a short C-terminal tail. The protein is highly expressed in skeletal and cardiac muscle. The protein links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle and may have a structural role in striated muscle. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]Chromosomal Location of Human Ortholog: 1p35.1 |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the intermediate filament family which contains an N-terminal head domain, followed by a central coiled-coil region and a short C-terminal tail. The protein is highly expressed in skeletal and cardiac muscle. The protein links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle and may have a structural role in striated muscle. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009] |
UniProt Code: | Q9H7C4 |
NCBI GenInfo Identifier: | 300669677 |
NCBI Gene ID: | 81493 |
NCBI Accession: | Q9H7C4.3 |
UniProt Secondary Accession: | Q9H7C4,B4DNK8, B4DY58, C9IY41 |
UniProt Related Accession: | Q9H7C4 |
Molecular Weight: | 54,947 Da |
NCBI Full Name: | Syncoilin |
NCBI Synonym Full Names: | syncoilin, intermediate filament protein |
NCBI Official Symbol: | SYNC |
NCBI Official Synonym Symbols: | SYNC1; SYNCOILIN |
NCBI Protein Information: | syncoilin |
UniProt Protein Name: | Syncoilin |
UniProt Synonym Protein Names: | Syncoilin intermediate filament 1; Syncoilin-1 |
Protein Family: | Syncoilin |
UniProt Gene Name: | SYNC |
UniProt Entry Name: | SYNCI_HUMAN |