SYN1 Polyclonal Antibody
- SKU:
- CAB5247
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | SYN1 Polyclonal Antibody |
| Product Code: | CAB5247 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples: | SH-SY5Y |
| Cellular Location: | Cell junction, Golgi apparatus, synapse |
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human SYN1 (NP_008881.2). |
| Sequence: | DEDKQ LIVEL VVNKM AQALP RQRQR DASPG RGSHG QTPSP GALPL GRQTS QQPAG PPAQQ RPPPQ GGPPQ PGPGP QRQGP PLQQR PPPQG QQHLS GLGPP A |
| Synonyms: | SYNI, EPILX, MRX50, SYN1a, SYN1b, EPILX1 |
| Calculated MW: | 74kDa |
| Observed MW: | 77kDa |
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