SYCE3 Antibody (PACO62131)
- SKU:
- PACO62131
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SYCE3 Antibody (PACO62131) |
| Antibody SKU: | PACO62131 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Synaptonemal complex central element protein 3 protein (1-88AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO62131 diluted at 1:300 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | IHC image of PACO62131 diluted at 1:300 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for chromosome loading of the central element-specific SCS proteins, and for initiating synapsis between homologous chromosomes. Chromosome loading appears to require SYCP1. Required for fertility. |
| Synonyms: | Synaptonemal complex central element protein 3 (Testis highly expressed gene 2 protein) (THEG-2), SYCE3, C22orf41 THEG2 |
| UniProt Protein Function: | SYCE3: Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for chromosome loading of the central element-specific SCS proteins, and for initiating synapsis between homologous chromosomes. Chromosome loading appears to require SYCP1. Required for fertility.Chromosomal Location of Human Ortholog: 22q13.33Cellular Component: central element; chromosome; nucleusBiological Process: synaptonemal complex assembly; cell division; positive regulation of apoptosis; meiotic recombination; spermatogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | A1L190 |
| NCBI GenInfo Identifier: | 178557813 |
| NCBI Gene ID: | 644186 |
| NCBI Accession: | NP_001116697.1 |
| UniProt Secondary Accession: | A1L190 |
| UniProt Related Accession: | A1L190 |
| Molecular Weight: | 10,601 Da |
| NCBI Full Name: | synaptonemal complex central element protein 3 |
| NCBI Synonym Full Names: | synaptonemal complex central element protein 3 |
| NCBI Official Symbol: | SYCE3 |
| NCBI Official Synonym Symbols: | THEG2; C22orf41 |
| NCBI Protein Information: | synaptonemal complex central element protein 3; testis highly expressed gene 2 protein; testis highly expressed protein 2 |
| UniProt Protein Name: | Synaptonemal complex central element protein 3 |
| UniProt Synonym Protein Names: | Testis highly expressed gene 2 protein; THEG-2 |
| Protein Family: | Synaptonemal complex central element protein |
| UniProt Gene Name: | SYCE3 |
| UniProt Entry Name: | SYCE3_HUMAN |
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