SUSD4 Antibody (PACO36606)
- SKU:
- PACO36606
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SUSD4 Antibody (PACO36606) |
| Antibody SKU: | PACO36606 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Sushi domain-containing protein 4 protein (56-290AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO36606 at dilution of 1:100. |
| Background: | Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways. |
| Synonyms: | Sushi domain-containing protein 4, SUSD4 |
| UniProt Protein Function: | SUSD4: 4 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 1q41Cellular Component: extracellular region; integral to membraneBiological Process: complement activation, classical pathway; innate immune response; negative regulation of complement activation, alternative pathway; negative regulation of complement activation, classical pathway; regulation of complement activation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q5VX71 |
| NCBI GenInfo Identifier: | 81295416 |
| NCBI Gene ID: | 55061 |
| NCBI Accession: | NP_001032252.1 |
| UniProt Secondary Accession: | Q5VX71,Q6UX62, Q9BSR0, Q9NWG0, D3DTB9 |
| UniProt Related Accession: | Q5VX71 |
| Molecular Weight: | 26,094 Da |
| NCBI Full Name: | sushi domain-containing protein 4 isoform b |
| NCBI Synonym Full Names: | sushi domain containing 4 |
| NCBI Official Symbol: | SUSD4 |
| NCBI Official Synonym Symbols: | PRO222 |
| NCBI Protein Information: | sushi domain-containing protein 4 |
| UniProt Protein Name: | Sushi domain-containing protein 4 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Sushi domain-containing protein |
| UniProt Gene Name: | SUSD4 |
| UniProt Entry Name: | SUSD4_HUMAN |
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