Survivin Monoclonal Antibody
- SKU:
- CAB22034
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Survivin Monoclonal Antibody |
| Product Code: | CAB22034 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC54647 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293F, Jurkat, HeLa |
| Cellular Location: | Chromosome, Cytoplasm, Midbody, Nucleus, Centromere, Cytoskeleton, Kinetochore, Spindle |
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human Survivin (NP_001159.2). |
| Sequence: | MGAPT LPPAW QPFLK DHRIS TFKNW PFLEG CACTP ERMAE AGFIH CPTEN EPDLA QCFFC FKELE GWEPD DDPIE EHKKH SSGCA FLSVK KQFEE LTLGE FLKLD RERAK NKIAK ETNNK KKEFE ETAEK VRRAI EQLAA MD |
| Synonyms: | API4, EPR-1 |
| Calculated MW: | 16kDa |
| Observed MW: | 18kDa |
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