Name: SULT1B1 Antibody (PACO17173)
SKU: PACO17173
Availability: OutOfStock

Antibody Name:	SULT1B1 Antibody (PACO17173)
Antibody SKU:	PACO17173
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:25-1:100
Species Reactivity:	Human
Immunogen:	Fusion protein of human SULT1B1

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17173(SULT1B1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal intestines tissue, Primary antibody: PACO17173(SULT1B1 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds.
	The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO17173(SULT1B1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).

Background:	Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. However, the total genomic length of this gene is greater than that of other SULT1 genes.
Synonyms:	sulfotransferase family, cytosolic, 1B, member 1

UniProt Protein Function:	SULT1B1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine, reverse triiodothyronine and thyroxine. Belongs to the sulfotransferase 1 family.
UniProt Protein Details:	Protein type:EC 2.8.2.-; Transferase Chromosomal Location of Human Ortholog: 4q13.3 Cellular Component: cytosol Molecular Function:sulfotransferase activity; aryl sulfotransferase activity Biological Process: steroid metabolic process; biogenic amine metabolic process; epithelial cell differentiation; flavonoid metabolic process; xenobiotic metabolic process; sulfation; 3'-phosphoadenosine 5'-phosphosulfate metabolic process; thyroid hormone metabolic process; phenol metabolic process
NCBI Summary:	Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. However, the total genomic length of this gene is greater than that of other SULT1 genes. [provided by RefSeq, Jul 2008]
UniProt Code:	O43704
NCBI GenInfo Identifier:	57013032
NCBI Gene ID:	27284
NCBI Accession:	O43704.2
UniProt Secondary Accession:	O43704,O15497, Q96FI1, Q9UK34,
UniProt Related Accession:	O43704
Molecular Weight:	296
NCBI Full Name:	Sulfotransferase family cytosolic 1B member 1
NCBI Synonym Full Names:	sulfotransferase family, cytosolic, 1B, member 1
NCBI Official Symbol:	SULT1B1
NCBI Official Synonym Symbols:	ST1B1; ST1B2; SULT1B2
NCBI Protein Information:	sulfotransferase family cytosolic 1B member 1; sulfotransferase 1B1; sulfotransferase 1B2; thyroid hormone sulfotransferase
UniProt Protein Name:	Sulfotransferase family cytosolic 1B member 1
UniProt Synonym Protein Names:	Sulfotransferase 1B2; ST1B2; Thyroid hormone sulfotransferase
Protein Family:	Sulfotransferase family cytosolic
UniProt Gene Name:	SULT1B1
UniProt Entry Name:	ST1B1_HUMAN