SULT1B1 Antibody (PACO17173)
- SKU:
- PACO17173
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SULT1B1 Antibody (PACO17173) |
| Antibody SKU: | PACO17173 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human SULT1B1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17173(SULT1B1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal intestines tissue, Primary antibody: PACO17173(SULT1B1 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO17173(SULT1B1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. However, the total genomic length of this gene is greater than that of other SULT1 genes. |
| Synonyms: | sulfotransferase family, cytosolic, 1B, member 1 |
| UniProt Protein Function: | SULT1B1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine, reverse triiodothyronine and thyroxine. Belongs to the sulfotransferase 1 family. |
| UniProt Protein Details: | Protein type:EC 2.8.2.-; Transferase Chromosomal Location of Human Ortholog: 4q13.3 Cellular Component: cytosol Molecular Function:sulfotransferase activity; aryl sulfotransferase activity Biological Process: steroid metabolic process; biogenic amine metabolic process; epithelial cell differentiation; flavonoid metabolic process; xenobiotic metabolic process; sulfation; 3'-phosphoadenosine 5'-phosphosulfate metabolic process; thyroid hormone metabolic process; phenol metabolic process |
| NCBI Summary: | Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. However, the total genomic length of this gene is greater than that of other SULT1 genes. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O43704 |
| NCBI GenInfo Identifier: | 57013032 |
| NCBI Gene ID: | 27284 |
| NCBI Accession: | O43704.2 |
| UniProt Secondary Accession: | O43704,O15497, Q96FI1, Q9UK34, |
| UniProt Related Accession: | O43704 |
| Molecular Weight: | 296 |
| NCBI Full Name: | Sulfotransferase family cytosolic 1B member 1 |
| NCBI Synonym Full Names: | sulfotransferase family, cytosolic, 1B, member 1 |
| NCBI Official Symbol: | SULT1B1 |
| NCBI Official Synonym Symbols: | ST1B1; ST1B2; SULT1B2 |
| NCBI Protein Information: | sulfotransferase family cytosolic 1B member 1; sulfotransferase 1B1; sulfotransferase 1B2; thyroid hormone sulfotransferase |
| UniProt Protein Name: | Sulfotransferase family cytosolic 1B member 1 |
| UniProt Synonym Protein Names: | Sulfotransferase 1B2; ST1B2; Thyroid hormone sulfotransferase |
| Protein Family: | Sulfotransferase family cytosolic |
| UniProt Gene Name: | SULT1B1 |
| UniProt Entry Name: | ST1B1_HUMAN |
| Antibodies |
| SULT1B1 Antibody (PACO12578) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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