sulA Antibody (PACO34930)
- SKU:
- PACO34930
- Product Type:
- Antibody
- Reactivity:
- Bacteria - Escherichia coli
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | sulA Antibody (PACO34930) |
| Antibody SKU: | PACO34930 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Escherichia coli |
| Immunogen: | Recombinant Escherichia coli Cell division inhibitor SulA protein (1-169AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. The effect of overexpression of SulA is neutralized by antitoxin CbeA (yeeU). |
| Synonyms: | Cell division inhibitor SulA, sulA, sfiA |
| UniProt Protein Function: | Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. The effect of overexpression of SulA is neutralized by antitoxin CbeA (yeeU) (PubMed:22515815). |
| UniProt Protein Details: | |
| NCBI Summary: | Regulation has been described . sulA mRNA stability during glucose starvation is diminished in the absence of |FRAME: [More information is available at EcoCyc: EG10984]. |
| UniProt Code: | P0AFZ5 |
| NCBI GenInfo Identifier: | 16128925 |
| NCBI Gene ID: | 947335 |
| NCBI Accession: | NP_415478.1 |
| UniProt Secondary Accession: | P0AFZ5,P03840, P08846, P71224 |
| UniProt Related Accession: | P0AFZ5 |
| Molecular Weight: | |
| NCBI Full Name: | SOS cell division inhibitor |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | sulA |
| NCBI Official Synonym Symbols: | ECK0949; JW0941; sfiA |
| NCBI Protein Information: | SOS cell division inhibitor |
| UniProt Protein Name: | Cell division inhibitor SulA |
| UniProt Synonym Protein Names: | |
| Protein Family: | Cell division inhibitor |
| UniProt Gene Name: | sulA |
| UniProt Entry Name: | SULA_ECOLI |
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