STXBP6 Antibody (PACO39706)
- SKU:
- PACO39706
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | STXBP6 Antibody (PACO39706) |
| Antibody SKU: | PACO39706 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Syntaxin-binding protein 6 protein (2-210AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: STXBP6 antibody at 2µg/ml + Mouse brain tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 24, 12 kDa. Observed band size: 24 kDa. |
 | Immunohistochemistry of paraffin-embedded human lung cancer using PACO39706 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO39706 at dilution of 1:100. |
| Background: | Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis. |
| Synonyms: | Syntaxin-binding protein 6 (Amisyn), STXBP6 |
| UniProt Protein Function: | STXBP6: Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 14q12 Cellular Component: exocyst; plasma membrane Molecular Function:GTP-Rho binding; phosphatidylinositol-4,5-bisphosphate binding Biological Process: exocyst localization; Golgi to plasma membrane transport; negative regulation of exocytosis |
| NCBI Summary: | STXBP6 binds components of the SNARE complex (see MIM 603215) and may be involved in regulating SNARE complex formation (Scales et al., 2002 [PubMed 12145319]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8NFX7 |
| NCBI GenInfo Identifier: | 34222907 |
| NCBI Gene ID: | 29091 |
| NCBI Accession: | Q8NFX7.2 |
| UniProt Secondary Accession: | Q8NFX7,Q8N3H1, Q8N8D5, Q96GF3, Q9P008, D3DS78, |
| UniProt Related Accession: | Q8NFX7 |
| Molecular Weight: | 11,587 Da |
| NCBI Full Name: | Syntaxin-binding protein 6 |
| NCBI Synonym Full Names: | syntaxin binding protein 6 |
| NCBI Official Symbol: | STXBP6 |
| NCBI Official Synonym Symbols: | amisyn; HSPC156 |
| NCBI Protein Information: | syntaxin-binding protein 6 |
| UniProt Protein Name: | Syntaxin-binding protein 6 |
| UniProt Synonym Protein Names: | Amisyn |
| Protein Family: | Syntaxin-binding protein |
| UniProt Gene Name: | STXBP6 |
| UniProt Entry Name: | STXB6_HUMAN |
| Antibodies |
| STXBP6 Antibody (PACO12568) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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