STRA8 Antibody (PACO18939)
- SKU:
- PACO18939
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | STRA8 Antibody (PACO18939) |
| Antibody SKU: | PACO18939 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human STRA8 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18939(STRA8 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO18939(STRA8 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene encodes a retinoic acid, responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans. |
| Synonyms: | stimulated by retinoic acid, 8 |
| UniProt Protein Function: | STRA8: Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase.Chromosomal Location of Human Ortholog: 7q33Cellular Component: cytoplasm; nucleusMolecular Function: protein dimerization activityBiological Process: fertilization; meiotic cell cycle DNA replication checkpoint; ovarian follicle development; meiotic chromosome condensation; meiotic recombination; synapsis; meiotic DNA double-strand break formation; spermatogenesis; regulation of organ growth; female meiosis sister chromatid cohesion; DNA replication; oocyte development |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans. [provided by RefSeq, Nov 2010] |
| UniProt Code: | Q7Z7C7 |
| NCBI GenInfo Identifier: | 74713759 |
| NCBI Gene ID: | 346673 |
| NCBI Accession: | Q7Z7C7.1 |
| UniProt Secondary Accession: | Q7Z7C7 |
| UniProt Related Accession: | Q7Z7C7 |
| Molecular Weight: | 36 kd |
| NCBI Full Name: | Stimulated by retinoic acid gene 8 protein homolog |
| NCBI Synonym Full Names: | stimulated by retinoic acid 8 |
| NCBI Official Symbol: | STRA8 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | stimulated by retinoic acid gene 8 protein homolog |
| UniProt Protein Name: | Stimulated by retinoic acid gene 8 protein homolog |
| UniProt Synonym Protein Names: | |
| Protein Family: | Stimulated by retinoic acid gene 8 protein |
| UniProt Gene Name: | STRA8 |
| UniProt Entry Name: | STRA8_HUMAN |
| Antibodies |
| STRA8 Antibody (PACO02222) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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