STON1 Antibody (PACO02388)
- SKU:
- PACO02388
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | STON1 Antibody |
| Antibody SKU: | PACO02388 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the C-terminal region of human Stonin-1. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | STON1; SALF; SBLF; STN1; Stonin-1; Stoned B-like factor |
| UniProt Protein Function: | STON1: May be involved in the endocytic machinery. Belongs to the Stoned B family.Chromosomal Location of Human Ortholog: 2p16.3Cellular Component: clathrin adaptor complexBiological Process: intracellular protein transport; regulation of endocytosis; endocytosis |
| UniProt Protein Details: | |
| NCBI Summary: | Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. This gene encodes one of two human homologs of the Drosophila melanogaster stoned B protein. This protein is related to components of the endocytic machinery and exhibits a modular structure consisting of an N-terminal proline-rich domain, a central region of homology specific to the human stoned B-like proteins, and a C-terminal region homologous to the mu subunits of adaptor protein (AP) complexes. Read-through transcription of this gene into the neighboring downstream gene, which encodes TFIIA-alpha/beta-like factor, generates a transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010] |
| UniProt Code: | Q9Y6Q2 |
| NCBI GenInfo Identifier: | 310703592 |
| NCBI Gene ID: | 11037 |
| NCBI Accession: | NP_001185522.1 |
| UniProt Secondary Accession: | Q9Y6Q2 |
| UniProt Related Accession: | Q9Y6Q2 |
| Molecular Weight: | ~ 83kDa |
| NCBI Full Name: | STON1-GTF2A1L protein isoform 2 |
| NCBI Synonym Full Names: | stonin 1 |
| NCBI Official Symbol: | STON1 |
| NCBI Official Synonym Symbols: | SALF; SBLF; STN1; STNB1 |
| NCBI Protein Information: | stonin-1 |
| UniProt Protein Name: | Stonin-1 |
| UniProt Synonym Protein Names: | Stoned B-like factor |
| Protein Family: | Stonin |
| UniProt Gene Name: | STON1 |
| UniProt Entry Name: | STON1_HUMAN |
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