Description
| Antibody Name: | STMN3 Antibody |
| Antibody SKU: | PACO01553 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the Internal region of human Stathmin-3. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | STMN3; SCLIP; Stathmin-3; SCG10-like protein |
| UniProt Protein Function: | STMN3: Exhibits microtubule-destabilizing activity, which is antagonized by STAT3. Belongs to the stathmin family. |
| UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 20q13.3 Cellular Component: cytoplasm; neuron projection Molecular Function:protein domain specific binding; tubulin binding Biological Process: cytoplasmic microtubule organization and biogenesis; microtubule depolymerization; negative regulation of Rac protein signal transduction; nervous system development; neurite development; regulation of cytoskeleton organization and biogenesis; regulation of GTPase activity |
| NCBI Summary: | This gene encodes a protein which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha- and beta-tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] |
| UniProt Code: | Q9NZ72 |
| NCBI GenInfo Identifier: | 20141809 |
| NCBI Gene ID: | 50861 |
| NCBI Accession: | Q9NZ72.3 |
| UniProt Secondary Accession: | Q9NZ72,O75527, Q969Y4, B3KSQ5, B7WP52, B7Z5G4, |
| UniProt Related Accession: | Q9NZ72 |
| Molecular Weight: | 19,806 Da |
| NCBI Full Name: | Stathmin-3 |
| NCBI Synonym Full Names: | stathmin 3 |
| NCBI Official Symbol: | STMN3 |
| NCBI Official Synonym Symbols: | SCLIP |
| NCBI Protein Information: | stathmin-3 |
| UniProt Protein Name: | Stathmin-3 |
| UniProt Synonym Protein Names: | SCG10-like protein |
| Protein Family: | Stathmin |
| UniProt Gene Name: | STMN3 |
| UniProt Entry Name: | STMN3_HUMAN |