| UniProt Protein Function: | DRAK1: a calmodulin-dependent kinase of the DAPK family. Interacts with and is regulated by calcineurin homologous protein (CHP), an EF-hand Ca(2+)-binding protein. In vitro, CHP inhibits the apoptosis-inducing protein kinase DRAK2 in the presence of elevated Ca(2+) levels. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.Protein type: Kinase, protein; Protein kinase, CAMK; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); CAMK group; DAPK familyChromosomal Location of Human Ortholog: 7p13Cellular Component: nucleusMolecular Function: protein serine/threonine kinase activity; ATP bindingBiological Process: apoptosis; positive regulation of apoptosis; protein amino acid phosphorylation |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UEE5 |
| NCBI GenInfo Identifier: | 109255245 |
| NCBI Gene ID: | 9263 |
| NCBI Accession: | NP_004751.2 |
| UniProt Secondary Accession: | Q9UEE5,Q8IVC8, A4D1V6 |
| UniProt Related Accession: | Q9UEE5 |
| Molecular Weight: | 46,558 Da |
| NCBI Full Name: | serine/threonine-protein kinase 17A |
| NCBI Synonym Full Names: | serine/threonine kinase 17a |
| NCBI Official Symbol: | STK17A |
| NCBI Official Synonym Symbols: | DRAK1 |
| NCBI Protein Information: | serine/threonine-protein kinase 17A; DAP kinase-related apoptosis-inducing protein kinase 1; death-associated protein kinase-related 1; serine/threonine kinase 17a (apoptosis-inducing) |
| UniProt Protein Name: | Serine/threonine-protein kinase 17A |
| UniProt Synonym Protein Names: | DAP kinase-related apoptosis-inducing protein kinase 1 |
| Protein Family: | |
| UniProt Gene Name: | STK17A |
| UniProt Entry Name: | ST17A_HUMAN |