Description
Antibody Name: | STK17A Antibody (PACO19581) |
Antibody SKU: | PACO19581 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human STK17A |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO19581(STK17A Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Raji cells, 293T cells, Primary antibody: PACO19581(STK17A Antibody) at dilution 1/900, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO19581(STK17A Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. |
Synonyms: | serine/threonine kinase 17a |
UniProt Protein Function: | DRAK1: a calmodulin-dependent kinase of the DAPK family. Interacts with and is regulated by calcineurin homologous protein (CHP), an EF-hand Ca(2+)-binding protein. In vitro, CHP inhibits the apoptosis-inducing protein kinase DRAK2 in the presence of elevated Ca(2+) levels. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.Protein type: Kinase, protein; Protein kinase, CAMK; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); CAMK group; DAPK familyChromosomal Location of Human Ortholog: 7p13Cellular Component: nucleusMolecular Function: protein serine/threonine kinase activity; ATP bindingBiological Process: apoptosis; positive regulation of apoptosis; protein amino acid phosphorylation |
UniProt Protein Details: | |
NCBI Summary: | This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UEE5 |
NCBI GenInfo Identifier: | 109255245 |
NCBI Gene ID: | 9263 |
NCBI Accession: | NP_004751.2 |
UniProt Secondary Accession: | Q9UEE5,Q8IVC8, A4D1V6 |
UniProt Related Accession: | Q9UEE5 |
Molecular Weight: | 46,558 Da |
NCBI Full Name: | serine/threonine-protein kinase 17A |
NCBI Synonym Full Names: | serine/threonine kinase 17a |
NCBI Official Symbol: | STK17A |
NCBI Official Synonym Symbols: | DRAK1 |
NCBI Protein Information: | serine/threonine-protein kinase 17A; DAP kinase-related apoptosis-inducing protein kinase 1; death-associated protein kinase-related 1; serine/threonine kinase 17a (apoptosis-inducing) |
UniProt Protein Name: | Serine/threonine-protein kinase 17A |
UniProt Synonym Protein Names: | DAP kinase-related apoptosis-inducing protein kinase 1 |
Protein Family: | |
UniProt Gene Name: | STK17A |
UniProt Entry Name: | ST17A_HUMAN |
Antibodies |
STK17A Antibody (PACO12529) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |