STARD8 Antibody (PACO17163)
- SKU:
- PACO17163
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | STARD8 Antibody (PACO17163) |
| Antibody SKU: | PACO17163 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human STARD8 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: A549 cells, Primary antibody: PACO17163(STARD8 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17163(STARD8 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | This gene encodes a member of a subfamily of Rho GTPase activating proteins that contain a steroidogenic acute regulatory protein related lipid transfer domain. The encoded protein localizes to focal adhesions and may be involved in regulating cell morphology. This protein may also function as a tumor suppressor. |
| Synonyms: | StAR-related lipid transfer (START) domain containing 8 |
| UniProt Protein Function: | STARD8: Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of phosphatidylinositol 4,5- bisphosphate by PLCD1. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:GAPs, Rac/Rho; GAPs Chromosomal Location of Human Ortholog: Xq13.1 Cellular Component: cytosol Molecular Function:GTPase activator activity Biological Process: regulation of small GTPase mediated signal transduction |
| NCBI Summary: | This gene encodes a member of a subfamily of Rho GTPase activating proteins that contain a steroidogenic acute regulatory protein related lipid transfer domain. The encoded protein localizes to focal adhesions and may be involved in regulating cell morphology. This protein may also function as a tumor suppressor. [provided by RefSeq, Mar 2010] |
| UniProt Code: | Q92502 |
| NCBI GenInfo Identifier: | 90110072 |
| NCBI Gene ID: | 9754 |
| NCBI Accession: | Q92502.2 |
| UniProt Secondary Accession: | Q92502,Q5JST0, Q68DG7, A8K6T2, D3DVT9, |
| UniProt Related Accession: | Q92502 |
| Molecular Weight: | 121,749 Da |
| NCBI Full Name: | StAR-related lipid transfer protein 8 |
| NCBI Synonym Full Names: | StAR related lipid transfer domain containing 8 |
| NCBI Official Symbol: | STARD8 |
| NCBI Official Synonym Symbols: | DLC3; ARHGAP38; STARTGAP3 |
| NCBI Protein Information: | stAR-related lipid transfer protein 8 |
| UniProt Protein Name: | StAR-related lipid transfer protein 8 |
| UniProt Synonym Protein Names: | Deleted in liver cancer 3 protein; DLC-3; START domain-containing protein 8; StARD8; START-GAP3 |
| Protein Family: | StAR-related lipid transfer protein |
| UniProt Gene Name: | STARD8 |
| UniProt Entry Name: | STAR8_HUMAN |
| Antibodies |
| STARD8 Antibody (PACO12509) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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