StAR Monoclonal Antibody
- SKU:
- CAB22166
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | StAR Monoclonal Antibody |
| Product Code: | CAB22166 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC55812 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:5000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | K-562, Mouse testis, Rat testis |
| Cellular Location: | Mitochondrion |
The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human StAR (NP_000340.2). |
| Sequence: | SQQDN GDKVM SKVVP DVGKV FRLEV VVDQP MERLY EELVE RMEAM GEWNP NVKEI KVLQK IGKDT FITHE LAAEA AGNLV GPRDF VSVRC AKRRG STCVL A |
| Synonyms: | STARD1 |
| Calculated MW: | 32kDa |
| Observed MW: | 28kDa |
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