ST8SIA5 Antibody (PACO30158)
- SKU:
- PACO30158
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ST8SIA5 Antibody (PACO30158) |
| Antibody SKU: | PACO30158 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Alpha-2,8-sialyltransferase 8E protein (101-376AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot Positive WB detected in: U87 whole cell lysate All lanes: ST8SIA5 antibody at 3.5µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 44, 48 kDa Observed band size: 44 kDa . |
 | Immunohistochemistry of paraffin-embedded human prostate cancer using PACO30158 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human liver cancer using PACO30158 at dilution of 1:100. |
| Background: | May be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b and GT3 from GD1a, GT1b, GM1b and GD3 respectively. |
| Synonyms: | Alpha-2,8-sialyltransferase 8E (EC 2.4.99.-) (Sialyltransferase 8E) (SIAT8-E) (Sialyltransferase St8Sia V) (ST8SiaV), ST8SIA5, SIAT8E |
| UniProt Protein Function: | ST8SIA5: May be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b and GT3 from GD1a, GT1b, GM1b and GD3 respectively. Belongs to the glycosyltransferase 29 family.Protein type: Membrane protein, integral; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; EC 2.4.99.-; TransferaseChromosomal Location of Human Ortholog: 18q21.1Cellular Component: Golgi membrane; integral to Golgi membraneMolecular Function: alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity; sialyltransferase activityBiological Process: glycosphingolipid biosynthetic process; cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; carbohydrate metabolic process; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a type II membrane protein that may be present in the Golgi apparatus. The encoded protein, which is a member of glycosyltransferase family 29, may be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b, and GT3 from GD1a, GT1b, GM1b, and GD3, respectively. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O15466 |
| NCBI GenInfo Identifier: | 28373101 |
| NCBI Gene ID: | 29906 |
| NCBI Accession: | NP_037437.2 |
| UniProt Secondary Accession: | O15466,Q6IAW7 |
| UniProt Related Accession: | O15466 |
| Molecular Weight: | 43,895 Da |
| NCBI Full Name: | alpha-2,8-sialyltransferase 8E |
| NCBI Synonym Full Names: | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| NCBI Official Symbol: | ST8SIA5 |
| NCBI Official Synonym Symbols: | SIAT8E; ST8SiaV |
| NCBI Protein Information: | alpha-2,8-sialyltransferase 8E; SIAT8-E; sialytransferase St8Sia V; sialyltransferase St8Sia V; sialyltransferase 8E (alpha-2, 8-polysialytransferase) |
| UniProt Protein Name: | Alpha-2,8-sialyltransferase 8E |
| UniProt Synonym Protein Names: | Sialyltransferase 8E; SIAT8-E; Sialyltransferase St8Sia V; ST8SiaV |
| Protein Family: | Alpha-2,8-sialyltransferase |
| UniProt Gene Name: | ST8SIA5 |
| UniProt Entry Name: | SIA8E_HUMAN |
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