ST6GALNAC3 Antibody (PACO38574)
- SKU:
- PACO38574
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ST6GALNAC3 Antibody (PACO38574) |
| Antibody SKU: | PACO38574 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 protein (40-305AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Involved in the biosynthesis of ganglioside GD1A from GM1B. Transfers CMP-NeuAc with an alpha-2,6-linkage to GalNAc residue on NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc of glycoproteins and glycolipids. ST6GalNAcIII prefers glycolipids to glycoproteins. |
| Synonyms: | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase III) (ST6GalNAc III) (ST6GalNAcIII) (STY) (Sialyltransferase 7C) (SIAT7-C), ST6GALNAC3, SIAT7C |
| UniProt Protein Function: | ST6GALNAC3: Involved in the biosynthesis of ganglioside GD1A from GM1B. Transfers CMP-NeuAc with an alpha-2,6-linkage to GalNAc residue on NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc of glycoproteins and glycolipids. ST6GalNAcIII prefers glycolipids to glycoproteins. Belongs to the glycosyltransferase 29 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Transferase; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; Membrane protein, integral; EC 2.4.99.-Chromosomal Location of Human Ortholog: 1p31.1Cellular Component: Golgi membrane; integral to membraneMolecular Function: sialyltransferase activityBiological Process: cellular protein metabolic process; glycoprotein metabolic process; dolichol-linked oligosaccharide biosynthetic process; glycosphingolipid metabolic process; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification; glycosylceramide metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | ST6GALNAC3 belongs to a family of sialyltransferases that transfer sialic acids from CMP-sialic acid to terminal positions of carbohydrate groups in glycoproteins and glycolipids (Lee et al., 1999 [PubMed 10207017]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8NDV1 |
| NCBI GenInfo Identifier: | 229892275 |
| NCBI Gene ID: | 256435 |
| NCBI Accession: | NP_001153483.1 |
| UniProt Secondary Accession: | Q8NDV1,Q6PCE0, Q6UX29, Q8N259 |
| UniProt Related Accession: | Q8NDV1 |
| Molecular Weight: | 24,022 Da |
| NCBI Full Name: | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 isoform 2 |
| NCBI Synonym Full Names: | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 |
| NCBI Official Symbol: | ST6GALNAC3 |
| NCBI Official Synonym Symbols: | STY; SIAT7C; PRO7177; ST6GALNACIII |
| NCBI Protein Information: | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; SIAT7-C; ST6GALNAC III; sialyltransferase 7C; GalNAc alpha-2,6-sialyltransferase III; alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase III; ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltran; sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) C |
| UniProt Protein Name: | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 |
| UniProt Synonym Protein Names: | GalNAc alpha-2,6-sialyltransferase III; ST6GalNAc III; ST6GalNAcIII; STY; Sialyltransferase 7C; SIAT7-C |
| Protein Family: | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase |
| UniProt Gene Name: | ST6GALNAC3 |
| UniProt Entry Name: | SIA7C_HUMAN |
Related Products
SIM1 Antibody
Overview Product Name:SIM1 AntibodyProduct Code:PACO64949Size:50µLTarget Names:SIM1Species Reactivity:HumanHost
eutC Antibody
Overview Product Name:eutC AntibodyProduct Code:PACO64709Size:50µLTarget Names:eutCSpecies Reactivity:Escherichia coli
EPHA10 Antibody
Overview Product Name:EPHA10 AntibodyProduct Code:PACO64693Size:50µLTarget Names:EPHA10Species Reactivity:HumanH
otsB Antibody
Overview Product Name:otsB AntibodyProduct Code:PACO64885Size:50µLTarget Names:otsBSpecies Reactivity:Escherichia coli
PCDHA8 Antibody
Overview Product Name:PCDHA8 AntibodyProduct Code:PACO64893Size:50µLTarget Names:PCDHA8Species Reactivity:HumanH