ST6GALNAC1 Antibody (PACO52758)
- SKU:
- PACO52758
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ST6GALNAC1 Antibody (PACO52758) |
| Antibody SKU: | PACO52758 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 protein (36-249AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: HepG2 whole cell lysate. All lanes: ST6GALNAC1 antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 69 kDa. Observed band size: 69 kDa. |
 | Immunohistochemistry of paraffin-embedded human skin tissue using PACO52758 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human melanoma using PACO52758 at dilution of 1:100. |
| Background: | Golgi membrane, alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity, sialyltransferase activity, ganglioside biosynthetic process, oligosaccharide metabolic process, protein glycosylation, protein N-linked glycosylation via asparagine |
| Synonyms: | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (ST6GalNAcI) (Sialyltransferase 7A) (SIAT7-A), ST6GALNAC1, SIAT7A |
| UniProt Protein Function: | ST6GALNAC1: Belongs to the glycosyltransferase 29 familyProtein type: Transferase; Membrane protein, integral; EC 2.4.99.3; Glycan Metabolism - O-glycan biosynthesisChromosomal Location of Human Ortholog: 17q25.1Cellular Component: Golgi membraneMolecular Function: alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activityBiological Process: ganglioside biosynthetic process; oligosaccharide metabolic process; protein amino acid N-linked glycosylation via asparagine |
| UniProt Protein Details: | |
| NCBI Summary: | Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9NSC7 |
| NCBI GenInfo Identifier: | 21759444 |
| NCBI Gene ID: | 55808 |
| NCBI Accession: | Q9NSC7.1 |
| UniProt Secondary Accession: | Q9NSC7,Q6UW90, Q9NSC6 |
| UniProt Related Accession: | Q9NSC7 |
| Molecular Weight: | 68,564 Da |
| NCBI Full Name: | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 |
| NCBI Synonym Full Names: | ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 |
| NCBI Official Symbol: | ST6GALNAC1 |
| NCBI Official Synonym Symbols: | STYI; SIAT7A; HSY11339; ST6GalNAcI |
| NCBI Protein Information: | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 |
| UniProt Protein Name: | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 |
| UniProt Synonym Protein Names: | GalNAc alpha-2,6-sialyltransferase I; ST6GalNAc I; ST6GalNAcI; Sialyltransferase 7A; SIAT7-A |
| Protein Family: | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase |
| UniProt Gene Name: | ST6GALNAC1 |
| UniProt Entry Name: | SIA7A_HUMAN |
| Antibodies |
| ST6GALNAC1 Antibody (PACO12492) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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