ST18 Antibody (PACO17159)
- SKU:
- PACO17159
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ST18 Antibody (PACO17159) |
| Antibody SKU: | PACO17159 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:40-1:150 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Fusion protein of human ST18 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO17159(ST18 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | ST18 (suppression of tumorigenicity 18), also known as ZNF387 ((zinc finger protein 387), is a 1,047 amino acid, nuclear protein that is expressed at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and prostate. Containing six C2HC-type zinc fingers and an SMC domain, ST18 is a repressor protein that binds to DNA sequences containing a specific bipartite element. ST18 is considered a transcription factor that represses basal transcription activity from target promoters and Inhibits colony formation in cultured breast cancer cells. |
| Synonyms: | suppression of tumorigenicity 18, zinc finger |
| UniProt Protein Function: | ST18: Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. Represses basal transcription activity from target promoters. Inhibits colony formation in cultured breast cancer cells.Chromosomal Location of Human Ortholog: 8q11.23Cellular Component: nucleusMolecular Function: DNA binding; zinc ion binding; transcription factor activityBiological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | O60284 |
| NCBI GenInfo Identifier: | 7662168 |
| NCBI Gene ID: | 9705 |
| NCBI Accession: | NP_055497.1 |
| UniProt Secondary Accession: | O60284 |
| UniProt Related Accession: | O60284 |
| Molecular Weight: | |
| NCBI Full Name: | suppression of tumorigenicity 18 protein isoform a |
| NCBI Synonym Full Names: | ST18 C2H2C-type zinc finger transcription factor |
| NCBI Official Symbol: | ST18 |
| NCBI Official Synonym Symbols: | NZF3; NZF-3; ZNF387; ZC2H2C3; ZC2HC10 |
| NCBI Protein Information: | suppression of tumorigenicity 18 protein |
| UniProt Protein Name: | Suppression of tumorigenicity 18 protein |
| UniProt Synonym Protein Names: | Zinc finger protein 387 |
| Protein Family: | Suppression of tumorigenicity 18 protein |
| UniProt Gene Name: | ST18 |
| UniProt Entry Name: | ST18_HUMAN |
| Antibodies |
| ST18 Antibody (PACO01545) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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