ST13 Monoclonal Antibody [PAT1F1AT] (CPAB0287)
![ST13 Monoclonal Antibody [PAT1F1AT] (CPAB0287)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58511/63693/st13-monoclonal-antibody-pat1f1at-cpab0287__03396__83071.1706535125.jpg?c=1 "ST13 Monoclonal Antibody [PAT1F1AT] (CPAB0287)")
- SKU:
- CPAB0287
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT1F1AT
- Applications:
- WB
- Applications:
- ELISA
![ST13 Monoclonal Antibody [PAT1F1AT] (CPAB0287)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58511/63693/st13-monoclonal-antibody-pat1f1at-cpab0287__03396__83071.1706535125.jpg?c=1&imbypass=on "ST13 Monoclonal Antibody [PAT1F1AT] (CPAB0287)")
Description
system_update_alt Datasheet
| Product Name: | ST13 Antibody |
| Product Sku: | CPAB0287 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human ST13 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human ST13 amino acids 1-369 purified from Ecoli. |
| Clone: | PAT1F1AT. |
| Reactivity: | Human |
| Applications: | Western Blot, ELISA |
| Purification Method: | ST13 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG1 |
| Background: | ST13 is an adaptor protein (co-chaperone) that mediates the association of HSP70 & HSP90 and appears in early receptor complexes. ST13 plays a role in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of ST13 is downregulated in colorectal carcinoma tissue signifying that is candidate tumor suppressor gene. Through common binding to both Hsp70 and Hsp90, ST13 functions as an adaptor that can integrate Hsp70 and Hsp90 interactions. The expression of ST13 decreases in colorectal cancer tissue compared with that in adjacent normal tissue. ST13 is mostly expressed in colorectal epithelia and adenocarcinoma cells. ST13 functions to promote the efficiency of glucocorticoid receptor maturation in cells. The expression levels of the ST13 gene were significantly decreased in primary tumors compared with adjacent mucosa. |
| Synonyms: | AAG2, SNC6, HSPABP, FAM10A1, FAM10A4, HSPABP1, ST-13, Hsc70-interacting protein, Suppression of tumorigenicity protein 13, Putative tumor suppressor ST13, Protein FAM10A1, Progesterone receptor-associated p48 protein, Renal carcinoma antigen NY-REN-33, ST13, HIP, HOP, P48, PRO0786, FLJ27260, MGC129952. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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