SSX2IP Antibody (PACO17155)
- SKU:
- PACO17155
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SSX2IP Antibody (PACO17155) |
| Antibody SKU: | PACO17155 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:30-1:150 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human SSX2IP |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO17155(SSX2IP Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO17155(SSX2IP Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. |
| Synonyms: | synovial sarcoma, X breakpoint 2 interacting protein |
| UniProt Protein Function: | SSX2IP: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E- cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Cell adhesionChromosomal Location of Human Ortholog: 1p22.3Cellular Component: protein complex; cell-cell adherens junction; leading edge; nucleusMolecular Function: protein domain specific binding; protein bindingBiological Process: regulation of Rac protein signal transduction; centrosome organization and biogenesis; cilium biogenesis; cell adhesion |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Oct 2009] |
| UniProt Code: | Q9Y2D8 |
| NCBI GenInfo Identifier: | 261878552 |
| NCBI Gene ID: | 117178 |
| NCBI Accession: | NP_001159889.1 |
| UniProt Secondary Accession: | Q9Y2D8,Q6P2P8, Q6ULS1, Q7L168, Q9UIX0, A8K8W0, B4DFE3 D3DT13, J3KR02 |
| UniProt Related Accession: | Q9Y2D8 |
| Molecular Weight: | 68,274 Da |
| NCBI Full Name: | afadin- and alpha-actinin-binding protein isoform 1 |
| NCBI Synonym Full Names: | synovial sarcoma, X breakpoint 2 interacting protein |
| NCBI Official Symbol: | SSX2IP |
| NCBI Official Synonym Symbols: | ADIP |
| NCBI Protein Information: | afadin- and alpha-actinin-binding protein; SSX2-interacting protein; afadin DIL domain-interacting protein |
| UniProt Protein Name: | Afadin- and alpha-actinin-binding protein |
| UniProt Synonym Protein Names: | Afadin DIL domain-interacting protein; SSX2-interacting protein |
| Protein Family: | Afadin- and alpha-actinin-binding protein |
| UniProt Gene Name: | SSX2IP |
| UniProt Entry Name: | ADIP_HUMAN |
| Antibodies |
| SSX2IP Antibody (PACO12483) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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