SRMS Antibody (PACO54182)
- SKU:
- PACO54182
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SRMS Antibody (PACO54182) |
| Antibody SKU: | PACO54182 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Tyrosine-protein kinase Srms protein (19-155AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry analysis of human breast cancer using PACO54182 at dilution of 1:100. |
 | Immunofluorescent analysis of MCF-7 cells using PACO54182 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues. May be involved in proliferation or differentiation of keratinocytes in the skin. |
| Synonyms: | Tyrosine-protein kinase Srms (EC 2.7.10.2), SRMS, C20orf148 |
| UniProt Protein Function: | SRMS: a tyrosine kinase of the Src family. Protein type: Protein kinase, tyrosine (non-receptor); Kinase, protein; EC 2.7.10.2; Motility/polarity/chemotaxis; Protein kinase, TK; TK group; Src familyChromosomal Location of Human Ortholog: -Cellular Component: cytoplasm; cytosol; extrinsic to internal side of plasma membraneMolecular Function: non-membrane spanning protein tyrosine kinase activity; protein binding; protein-tyrosine kinase activity; receptor bindingBiological Process: cell differentiation; cell migration; innate immune response; negative regulation of signal transduction; regulation of cell proliferation; transmembrane receptor protein tyrosine kinase signaling pathway |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9H3Y6 |
| NCBI GenInfo Identifier: | 27805732 |
| NCBI Gene ID: | 6725 |
| NCBI Accession: | Q9H3Y6.1 |
| UniProt Secondary Accession: | Q9H3Y6 |
| UniProt Related Accession: | Q9H3Y6 |
| Molecular Weight: | 54,507 Da |
| NCBI Full Name: | Tyrosine-protein kinase Srms |
| NCBI Synonym Full Names: | src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites |
| NCBI Official Symbol: | SRMS |
| NCBI Official Synonym Symbols: | SRM; PTK70; C20orf148; dJ697K14.1 |
| NCBI Protein Information: | tyrosine-protein kinase Srms |
| UniProt Protein Name: | Tyrosine-protein kinase Srms |
| UniProt Synonym Protein Names: | |
| Protein Family: | Tyrosine-protein kinase |
| UniProt Gene Name: | SRMS |
| UniProt Entry Name: | SRMS_HUMAN |
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