SQSTM1/p62 Polyclonal Antibody (CAB21702)
- SKU:
- CAB21702
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Applications:
- IP
Description
| Product Name: | SQSTM1/p62 Polyclonal Antibody |
| Product Code: | CAB21702 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, IP, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation |
| Recommended Dilution: | WB 1:2000-1:4000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200, IP 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, HeLa, L929, PC-12 |
| Cellular Location: | Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Late endosome, Lysosome, Nucleus, P-body, autophagosome |
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 340-440 of human SQSTM1/p62. (NP_003891.1). |
| Sequence: | HLSSK EVDPS TGELQ SLQMP ESEGP SSLDP SQEGP TGLKE AALYP HLPPE ADPRL IESLS QMLSM GFSDE GGWLT RLLQT KNYDI GAALD TIQYS KHPPP L |
| Synonyms: | p60, p62, A170, DMRV, OSIL, PDB3, ZIP3, p62B, NADGP, FTDALS3 |
| Calculated MW: | 48kDa |
| Observed MW: | 62kDa |
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