SPTBN2 Antibody (PACO12445)
- SKU:
- PACO12445
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SPTBN2 Antibody (PACO12445) |
| Antibody SKU: | PACO12445 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Human SPTBN2 |
| Form: | Liquid |
| Storage Buffer: | 0.1M NaHCO3,0.1M Glycine, 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | spectrin, beta, non-erythrocytic 2;SPTBN2;GTRAP41;SCA5 ; |
| UniProt Protein Function: | Probably plays an important role in neuronal membrane skeleton. |
| UniProt Protein Details: | |
| NCBI Summary: | Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009] |
| UniProt Code: | O15020 |
| NCBI GenInfo Identifier: | 5902122 |
| NCBI Gene ID: | 6712 |
| NCBI Accession: | NP_008877.1 |
| UniProt Secondary Accession: | O15020 |
| UniProt Related Accession: | O15020 |
| Molecular Weight: | 246kDa |
| NCBI Full Name: | spectrin beta chain, non-erythrocytic 2 |
| NCBI Synonym Full Names: | spectrin beta, non-erythrocytic 2 |
| NCBI Official Symbol: | SPTBN2 |
| NCBI Official Synonym Symbols: | SCA5; SCAR14; GTRAP41 |
| NCBI Protein Information: | spectrin beta chain, non-erythrocytic 2 |
| UniProt Protein Name: | Spectrin beta chain, non-erythrocytic 2 |
| UniProt Synonym Protein Names: | Beta-III spectrin; Spinocerebellar ataxia 5 protein |
| Protein Family: | Spectrin |
| UniProt Gene Name: | SPTBN2 |
| UniProt Entry Name: |
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