SPT16 Antibody (PACO30226)
- SKU:
- PACO30226
- Product Type:
- Antibody
- Reactivity:
- Plant - Arabidopsis
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SPT16 Antibody (PACO30226) |
| Antibody SKU: | PACO30226 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Arabidopsis thaliana |
| Immunogen: | Recombinant Arabidopsis thaliana FACT complex subunit SPT16 protein (890-1074AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (Probable). |
| Synonyms: | FACT complex subunit SPT16 (Facilitates chromatin transcription complex subunit SPT16), SPT16 |
| UniProt Protein Function: | Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (Probable). |
| UniProt Protein Details: | |
| NCBI Summary: | encodes a component of the FAcilitates Chromatin Transcription (FACT) complex, SPT16.Along with SSRP1 binds to the promoter of FLC. |
| UniProt Code: | O82491 |
| NCBI GenInfo Identifier: | 15236899 |
| NCBI Gene ID: | 826665 |
| NCBI Accession: | NP_192809.1 |
| UniProt Secondary Accession: | O82491,C0SVH5 |
| UniProt Related Accession: | O82491 |
| Molecular Weight: | |
| NCBI Full Name: | FACT complex subunit SPT16 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | SPT16 |
| NCBI Official Synonym Symbols: | global transcription factor C; SPT16; T12H20.3; T12H20_3 |
| NCBI Protein Information: | FACT complex subunit SPT16 |
| UniProt Protein Name: | FACT complex subunit SPT16 |
| UniProt Synonym Protein Names: | Facilitates chromatin transcription complex subunit SPT16 |
| Protein Family: | FACT complex |
| UniProt Gene Name: | SPT16 |
| UniProt Entry Name: | SPT16_ARATH |
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