SPOCK1 Antibody (PACO46618)
- SKU:
- PACO46618
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SPOCK1 Antibody (PACO46618) |
| Antibody SKU: | PACO46618 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Testican-1 protein (290-435AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO46618 at dilution of 1:100. |
 | Western Blot. Positive WB detected in: Mouse brain tissue. All lanes: SPOCK1 antibody at 1:3000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 50 kDa. Observed band size: 50 kDa. |
 | Immunofluorescent analysis of HepG2 cells using PACO46618 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | May play a role in cell-cell and cell-matrix interactions. May contribute to various neuronal mechanisms in the central nervous system. |
| Synonyms: | Testican-1 (Protein SPOCK), SPOCK1, SPOCK TIC1 TICN1 |
| UniProt Protein Function: | SPOCK1: May play a role in cell-cell and cell-matrix interactions. May contribute to various neuronal mechanisms in the central nervous system.Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide; Cell adhesionChromosomal Location of Human Ortholog: 5q31.2Cellular Component: proteinaceous extracellular matrix; extracellular space; postsynaptic density; cytoplasm; neuromuscular junction; sarcoplasmMolecular Function: serine-type endopeptidase inhibitor activity; metalloendopeptidase inhibitor activity; calcium ion binding; cysteine protease inhibitor activityBiological Process: nervous system development; central nervous system neuron differentiation; neurogenesis; neuron migration; regulation of cell growth; signal transduction; cell adhesion |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q08629 |
| NCBI GenInfo Identifier: | 4759164 |
| NCBI Gene ID: | 6695 |
| NCBI Accession: | NP_004589.1 |
| UniProt Secondary Accession: | Q08629,Q59EW0, Q8N630, Q9UCL8, B3KSW3 |
| UniProt Related Accession: | Q08629 |
| Molecular Weight: | 49,124 Da |
| NCBI Full Name: | testican-1 |
| NCBI Synonym Full Names: | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| NCBI Official Symbol: | SPOCK1 |
| NCBI Official Synonym Symbols: | TIC1; SPOCK; TESTICAN |
| NCBI Protein Information: | testican-1 |
| UniProt Protein Name: | Testican-1 |
| UniProt Synonym Protein Names: | Protein SPOCK |
| Protein Family: | |
| UniProt Gene Name: | SPOCK1 |
| UniProt Entry Name: | TICN1_HUMAN |
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