SPNS2 Antibody (PACO46794)
- SKU:
- PACO46794
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SPNS2 Antibody (PACO46794) |
| Antibody SKU: | PACO46794 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Protein spinster homolog 2 protein (1-140AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of HepG2 cells using PACO46794 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Sphingolipid transporter required for migration of myocardial precursors. Transports sphingosine 1-phosphate (S1P), a secreted lipid mediator that plays critical roles in cardiovascular, immunological, and neural development and function. Mediates the export of S1P from cells in the extraembryonic yolk syncytial layer (YSL), thereby regulating myocardial precursor migration. |
| Synonyms: | Protein spinster homolog 2, SPNS2 |
| UniProt Protein Function: | SPNS2: Sphingolipid transporter required for migration of myocardial precursors. Transports sphingosine 1-phosphate (S1P), a secreted lipid mediator that plays critical roles in cardiovascular, immunological, and neural development and function. Mediates the export of S1P from cells in the extraembryonic yolk syncytial layer (YSL), thereby regulating myocardial precursor migration. Belongs to the major facilitator (TC 2.A.1) superfamily. Spinster (TC 2.A.1.49) family.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 17p13.2Cellular Component: lysosomal membrane; vesicleMolecular Function: sphingolipid transporter activityBiological Process: locomotion |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a transporter of sphingosine 1-phosphate, a secreted lipid that is important in cardiovascular, immunological, and neural development. Defects in this gene are a cause of early onset progressive hearing loss. [provided by RefSeq, Jul 2016] |
| UniProt Code: | Q8IVW8 |
| NCBI GenInfo Identifier: | 121947811 |
| NCBI Gene ID: | 124976 |
| NCBI Accession: | Q8IVW8.2 |
| UniProt Secondary Accession: | Q8IVW8,B9A1T3 |
| UniProt Related Accession: | Q8IVW8 |
| Molecular Weight: | 58,044 Da |
| NCBI Full Name: | Protein spinster homolog 2 |
| NCBI Synonym Full Names: | sphingolipid transporter 2 |
| NCBI Official Symbol: | SPNS2 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | protein spinster homolog 2 |
| UniProt Protein Name: | Protein spinster homolog 2 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Protein spinster |
| UniProt Gene Name: | SPNS2 |
| UniProt Entry Name: | SPNS2_HUMAN |
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