SPIRE1 Antibody (PACO12437)
- SKU:
- PACO12437
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SPIRE1 Antibody (PACO12437) |
| Antibody SKU: | PACO12437 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human SPIRE1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | spire homolog 1 (Drosophila);SPIRE1;MGC150621;MGC150622;Spir-1 ; |
| UniProt Protein Function: | SPIRE1: Acts as a actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in vesicle transport processes providing a novel link between actin organization and intracellular transport. Belongs to the spire family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: CytoskeletalChromosomal Location of Human Ortholog: 18p11.21Cellular Component: cell cortex; cleavage furrow; cytoplasmic vesicle membraneBiological Process: actin cytoskeleton organization and biogenesis; establishment of meiotic spindle localization; intracellular transport; polar body extrusion after meiotic divisions; vesicle-mediated transport |
| UniProt Protein Details: | |
| NCBI Summary: | Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001 [PubMed 11747823]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q08AE8 |
| NCBI GenInfo Identifier: | 425906061 |
| NCBI Gene ID: | 56907 |
| NCBI Accession: | Q08AE8.3 |
| UniProt Secondary Accession: | Q08AE8,Q1RMD4, Q8NDP1, Q9NQ71, Q9ULT4, A8K2B5, J3KQ50 J3KQR5 |
| UniProt Related Accession: | Q08AE8 |
| Molecular Weight: | 52,747 Da |
| NCBI Full Name: | Protein spire homolog 1 |
| NCBI Synonym Full Names: | spire type actin nucleation factor 1 |
| NCBI Official Symbol: | SPIRE1 |
| NCBI Official Synonym Symbols: | Spir-1 |
| NCBI Protein Information: | protein spire homolog 1 |
| UniProt Protein Name: | Protein spire homolog 1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Protein spire |
| UniProt Gene Name: | SPIRE1 |
| UniProt Entry Name: | SPIR1_HUMAN |
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