SPINK6 Antibody (PACO57220)
- SKU:
- PACO57220
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SPINK6 Antibody (PACO57220) |
| Antibody SKU: | PACO57220 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Serine protease inhibitor Kazal-type 6 protein (24-80AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO57220 diluted at 1:400 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | IHC image of PACO57220 diluted at 1:400 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Serine protease inhibitor selective for kallikreins. Efficiently inhibits KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14. Doesn't inhibit KLK8. |
| Synonyms: | Serine protease inhibitor Kazal-type 6 (Kallikrein inhibitor), SPINK6 |
| UniProt Protein Function: | SPINK6: Serine protease inhibitor selective for kallikreins. Efficiently inhibits KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14. Doesn't inhibit KLK8.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 5q32Cellular Component: extracellular regionMolecular Function: serine-type endopeptidase inhibitor activity |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a Kazal-type serine protease inhibitor that acts on kallikrein-related peptidases in the skin. Two transcript variants the same protein have been found for this gene. [provided by RefSeq, Aug 2010] |
| UniProt Code: | Q6UWN8 |
| NCBI GenInfo Identifier: | 305632839 |
| NCBI Gene ID: | 404203 |
| NCBI Accession: | NP_001182219.1 |
| UniProt Secondary Accession: | Q6UWN8,Q8N5P0, E0X656 |
| UniProt Related Accession: | Q6UWN8 |
| Molecular Weight: | 8,585 Da |
| NCBI Full Name: | serine protease inhibitor Kazal-type 6 |
| NCBI Synonym Full Names: | serine peptidase inhibitor, Kazal type 6 |
| NCBI Official Symbol: | SPINK6 |
| NCBI Official Synonym Symbols: | BUSI2; UNQ844 |
| NCBI Protein Information: | serine protease inhibitor Kazal-type 6; acrosin inhibitor; kallikrein inhibitor; protease inhibitor H |
| UniProt Protein Name: | Serine protease inhibitor Kazal-type 6 |
| UniProt Synonym Protein Names: | Kallikrein inhibitor |
| Protein Family: | Serine protease inhibitor |
| UniProt Gene Name: | SPINK6 |
| UniProt Entry Name: | ISK6_HUMAN |
| Antibodies |
| SPINK6 Antibody (PACO04253) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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