SPIC Transcription Factor Activity Assay
- SKU:
- TFAB00103
- Product Type:
- ELISA Kit
- ELISA Type:
- Transcription Factor Assay
- Analytes:
- SPIC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
Description
system_update_altDatasheet
| Product Name: | SPIC Transcription Factor Activity Assay |
| Product Code: | TFAB00103 |
| Target: | SPIC |
| Reactivity: | Human, Mouse, Rat |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie SPIC transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | SPIC: Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression. Belongs to the ETS family. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 12q23.2 Cellular Component: nucleus Biological Process: cell differentiation; regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | The protein encoded by this gene regulates the development of red pulp macrophages, which are necessary for iron homeostasis and the recycling of red blood cells. [provided by RefSeq, Aug 2016] |
| UniProt Code: | Q8N5J4 |
| NCBI GenInfo Identifier: | 22748707 |
| NCBI Gene ID: | 121599 |
| NCBI Accession: | NP_689536.1 |
| UniProt Related Accession: | Q8N5J4 |
| Molecular Weight: | 29kd |
| NCBI Full Name: | transcription factor Spi-C |
| NCBI Synonym Full Names: | Spi-C transcription factor |
| NCBI Official Symbol: | SPIC |
| NCBI Official Synonym Symbols: | SPI-C |
| NCBI Protein Information: | transcription factor Spi-C |
| UniProt Protein Name: | Transcription factor Spi-C |
| Protein Family: | SpiC |
| UniProt Gene Name: | SPIC |
| UniProt Entry Name: | SPIC_HUMAN |
