SPIC Antibody (PACO21897)
- SKU:
- PACO21897
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SPIC Antibody (PACO21897) |
| Antibody SKU: | PACO21897 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from internal of human SPIC. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Clonality: | Polyclonal |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from HepG2 cells and HeLa cells, using SPIC antibody. |
| Synonyms: | Transcription factor Spi-C; SPIC; |
| UniProt Protein Function: | SPIC: Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression. Belongs to the ETS family. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 12q23.2 Cellular Component: nucleus Biological Process: cell differentiation; regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | The protein encoded by this gene regulates the development of red pulp macrophages, which are necessary for iron homeostasis and the recycling of red blood cells. [provided by RefSeq, Aug 2016] |
| UniProt Code: | Q8N5J4 |
| NCBI GenInfo Identifier: | 22748707 |
| NCBI Gene ID: | 121599 |
| NCBI Accession: | NP_689536.1 |
| UniProt Related Accession: | Q8N5J4 |
| Molecular Weight: | 29kd |
| NCBI Full Name: | transcription factor Spi-C |
| NCBI Synonym Full Names: | Spi-C transcription factor |
| NCBI Official Symbol: | SPIC |
| NCBI Official Synonym Symbols: | SPI-C |
| NCBI Protein Information: | transcription factor Spi-C |
| UniProt Protein Name: | Transcription factor Spi-C |
| Protein Family: | SpiC |
| UniProt Gene Name: | SPIC |
| UniProt Entry Name: | SPIC_HUMAN |
| Antibodies | ELISA Kits |
| SPIC Antibody (PACO01529) | SPIC Transcription Factor Activity Assay |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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