Description
Antibody Name: | SPCS2 Antibody (PACO35458) |
Antibody SKU: | PACO35458 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Signal peptidase complex subunit 2 protein (7-86AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human colon cancer using PACO35458 at dilution of 1:100. |
![]() | Immunofluorescent analysis of Hela cells using PACO35458 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO35458 at dilution of 1:100. |
Background: | Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. |
Synonyms: | Signal peptidase complex subunit 2 (EC 3.4.-.-) (Microsomal signal peptidase 25 kDa subunit) (SPase 25 kDa subunit), SPCS2, KIAA0102 SPC25 |
UniProt Protein Function: | SPCS2: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the SPCS2 family.Protein type: EC 3.4.-.-; Protease; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 11q13.4Cellular Component: endoplasmic reticulum membrane; integral to membrane; signal peptidase complexMolecular Function: peptidase activityBiological Process: protein targeting to ER; signal peptide processing |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q15005 |
NCBI GenInfo Identifier: | 162417971 |
NCBI Gene ID: | 9789 |
NCBI Accession: | NP_055567.2 |
UniProt Secondary Accession: | Q15005,Q15507, Q3KQT0, Q641R4, Q6FG65, Q6IRX0, Q6P1P4 Q96HU9 |
UniProt Related Accession: | Q15005 |
Molecular Weight: | 25,003 Da |
NCBI Full Name: | signal peptidase complex subunit 2 |
NCBI Synonym Full Names: | signal peptidase complex subunit 2 |
NCBI Official Symbol: | SPCS2 |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | signal peptidase complex subunit 2 |
UniProt Protein Name: | Signal peptidase complex subunit 2 |
UniProt Synonym Protein Names: | Microsomal signal peptidase 25 kDa subunit; SPase 25 kDa subunit |
Protein Family: | Signal peptidase complex |
UniProt Gene Name: | SPCS2 |
UniProt Entry Name: | SPCS2_HUMAN |
Antibodies |
SPCS2 Antibody (PACO12428) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |