SPCS1 Antibody (PACO42642)
- SKU:
- PACO42642
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SPCS1 Antibody (PACO42642) |
| Antibody SKU: | PACO42642 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Signal peptidase complex subunit 1 protein (70-102AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of MCF-7 cells using PACO42642 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. |
| Synonyms: | Signal peptidase complex subunit 1 (EC 3.4.-.-) (Microsomal signal peptidase 12 kDa subunit) (SPase 12 kDa subunit), SPCS1, SPC12 |
| UniProt Protein Function: | SPCS1: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the SPCS1 family. |
| UniProt Protein Details: | Protein type:Protease; Endoplasmic reticulum; Amino Acid Metabolism - lysine degradation; Cofactor and Vitamin Metabolism - biotin; Membrane protein, multi-pass; EC 3.4.-.-; Membrane protein, integral Chromosomal Location of Human Ortholog: 3p21.1 Cellular Component: endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; signal peptidase complex Molecular Function:peptidase activity; protein binding Biological Process: protein targeting to ER; SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; signal peptide processing; translation; gene expression; proteolysis; regulation of insulin secretion |
| UniProt Code: | Q9Y6A9 |
| NCBI GenInfo Identifier: | 557952606 |
| NCBI Gene ID: | 28972 |
| NCBI Accession: | Q9Y6A9.4 |
| UniProt Secondary Accession: | Q9Y6A9,Q9BVW1, B3KNF8, |
| UniProt Related Accession: | Q9Y6A9 |
| Molecular Weight: | 169 |
| NCBI Full Name: | Signal peptidase complex subunit 1 |
| NCBI Synonym Full Names: | signal peptidase complex subunit 1 homolog (S. cerevisiae) |
| NCBI Official Symbol: | SPCS1 |
| NCBI Official Synonym Symbols: | SPC1; SPC12; HSPC033; YJR010C-A |
| NCBI Protein Information: | signal peptidase complex subunit 1; SPase 12 kDa subunit; signal peptidase 12kDa; microsomal signal peptidase 12 kDa subunit |
| UniProt Protein Name: | Signal peptidase complex subunit 1 |
| UniProt Synonym Protein Names: | Microsomal signal peptidase 12 kDa subunit; SPase 12 kDa subunit |
| Protein Family: | Signal peptidase complex |
| UniProt Gene Name: | SPCS1 |
| UniProt Entry Name: | SPCS1_HUMAN |
| Antibodies |
| SPCS1 Antibody (PACO12427) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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