Description
| Antibody Name: | SPCS1 Antibody (PACO12427) |
| Antibody SKU: | PACO12427 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human SPCS1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | signal peptidase complex subunit 1 homolog (S. cerevisiae);SPCS1;HSPC033;SPC1;SPC12;YJR010C-A ; |
| UniProt Protein Function: | SPCS1: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the SPCS1 family. |
| UniProt Protein Details: | Protein type:Protease; Endoplasmic reticulum; Amino Acid Metabolism - lysine degradation; Cofactor and Vitamin Metabolism - biotin; Membrane protein, multi-pass; EC 3.4.-.-; Membrane protein, integral Chromosomal Location of Human Ortholog: 3p21.1 Cellular Component: endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; signal peptidase complex Molecular Function:peptidase activity; protein binding Biological Process: protein targeting to ER; SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; signal peptide processing; translation; gene expression; proteolysis; regulation of insulin secretion |
| UniProt Code: | Q9Y6A9 |
| NCBI GenInfo Identifier: | 557952606 |
| NCBI Gene ID: | 28972 |
| NCBI Accession: | Q9Y6A9.4 |
| UniProt Secondary Accession: | Q9Y6A9,Q9BVW1, B3KNF8, |
| UniProt Related Accession: | Q9Y6A9 |
| Molecular Weight: | 169 |
| NCBI Full Name: | Signal peptidase complex subunit 1 |
| NCBI Synonym Full Names: | signal peptidase complex subunit 1 homolog (S. cerevisiae) |
| NCBI Official Symbol: | SPCS1 |
| NCBI Official Synonym Symbols: | SPC1; SPC12; HSPC033; YJR010C-A |
| NCBI Protein Information: | signal peptidase complex subunit 1; SPase 12 kDa subunit; signal peptidase 12kDa; microsomal signal peptidase 12 kDa subunit |
| UniProt Protein Name: | Signal peptidase complex subunit 1 |
| UniProt Synonym Protein Names: | Microsomal signal peptidase 12 kDa subunit; SPase 12 kDa subunit |
| Protein Family: | Signal peptidase complex |
| UniProt Gene Name: | SPCS1 |
| UniProt Entry Name: | SPCS1_HUMAN |