SPATA20 Antibody (PACO18921)
- SKU:
- PACO18921
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SPATA20 Antibody (PACO18921) |
| Antibody SKU: | PACO18921 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human SPATA20 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18921(SPATA20 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 10%SDS-PAGE, Lysate: 60 μg, Lane 1-3: A549 cells, lncap cells, human seminoma tissue, Primary antibody: PACO18921(SPATA20 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO18921(SPATA20 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | The protein may play a role in fertility regulation. It were significantly upregulated in individual bile samples from Cholangiocarcinoma patients by Western blotting and Immunohistochemistry, relative to normal tissues.It acts as a potential serum diagnostic biomarker for Cholangiocarcinoma. |
| Synonyms: | spermatogenesis associated 20 |
| UniProt Protein Function: | SPATA20: May play a role in fertility regulation. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 17q21.33Cellular Component: extracellular regionMolecular Function: catalytic activityBiological Process: metabolic process; multicellular organismal development; spermatogenesis; cell differentiation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8TB22 |
| NCBI GenInfo Identifier: | 84040225 |
| NCBI Gene ID: | 64847 |
| NCBI Accession: | AAI11030.1 |
| UniProt Secondary Accession: | Q8TB22,Q2TA99, Q2XUZ6, Q6P0P1, Q8WVW3, Q9H747 |
| UniProt Related Accession: | Q8TB22 |
| Molecular Weight: | |
| NCBI Full Name: | SPATA20 protein |
| NCBI Synonym Full Names: | spermatogenesis associated 20 |
| NCBI Official Symbol: | SPATA20 |
| NCBI Official Synonym Symbols: | SSP411; Tisp78 |
| NCBI Protein Information: | spermatogenesis-associated protein 20; sperm protein SSP411; sperm-specific protein 411; transcript increased in spermiogenesis 78 |
| UniProt Protein Name: | Spermatogenesis-associated protein 20 |
| UniProt Synonym Protein Names: | Sperm-specific protein 411; Ssp411 |
| Protein Family: | Spermatogenesis-associated protein |
| UniProt Gene Name: | SPATA20 |
| UniProt Entry Name: | SPT20_HUMAN |
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