Description
Antibody Name: | SPANXC Antibody (PACO41478) |
Antibody SKU: | PACO41478 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Sperm protein associated with the nucleus on the X chromosome C protein (1-97AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human skin tissue using PACO41478 at dilution of 1:100. |
Background: | nucleus |
Synonyms: | Sperm protein associated with the nucleus on the X chromosome C (Cancer/testis antigen 11.3) (CT11.3) (Cancer/testis-associated protein CTp11) (Nuclear-associated protein SPAN-Xc) (SPANX-C) (SPANX family member C), SPANXC |
UniProt Protein Function: | SPANXC: Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy. [provided by RefSeq, Jul 2008]Protein type: Cancer Testis Antigen (CTA)Chromosomal Location of Human Ortholog: Xq27.1Cellular Component: cytoplasm; nucleus |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9NY87 |
NCBI GenInfo Identifier: | 85543354 |
NCBI Gene ID: | |
NCBI Accession: | Q9NY87.1 |
UniProt Secondary Accession: | Q9NY87,Q32WL9, Q5JX88 |
UniProt Related Accession: | Q9NY87 |
Molecular Weight: | 11,002 Da |
NCBI Full Name: | Sperm protein associated with the nucleus on the X chromosome C |
NCBI Synonym Full Names: | |
NCBI Official Symbol: | |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | |
UniProt Protein Name: | Sperm protein associated with the nucleus on the X chromosome C |
UniProt Synonym Protein Names: | Cancer/testis antigen 11.3; CT11.3; Cancer/testis-associated protein CTp11; Nuclear-associated protein SPAN-Xc; SPANX-C; SPANX family member C |
Protein Family: | Sperm protein associated with the nucleus on the X chromosome |
UniProt Gene Name: | SPANXC |
UniProt Entry Name: | SPNXC_HUMAN |
Antibodies |
SPANXC Antibody (PACO12418) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |