SPACA1 Antibody (PACO40610)
- SKU:
- PACO40610
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SPACA1 Antibody (PACO40610) |
| Antibody SKU: | PACO40610 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Sperm acrosome membrane-associated protein 1 protein (30-221AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO40610 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO40610 at dilution of 1:100. |
| Background: | May be involved in sperm-egg fusion. |
| Synonyms: | Sperm acrosome membrane-associated protein 1 (Sperm acrosomal membrane-associated protein 32), SPACA1, SAMP32 |
| UniProt Protein Function: | SPACA1: May be involved in sperm-egg fusion.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 6q15Cellular Component: acrosomal membraneBiological Process: acrosome formation |
| UniProt Protein Details: | |
| NCBI Summary: | The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9HBV2 |
| NCBI GenInfo Identifier: | 74752784 |
| NCBI Gene ID: | 81833 |
| NCBI Accession: | Q9HBV2.1 |
| UniProt Secondary Accession: | Q9HBV2 |
| UniProt Related Accession: | Q9HBV2 |
| Molecular Weight: | 32,143 Da |
| NCBI Full Name: | Sperm acrosome membrane-associated protein 1 |
| NCBI Synonym Full Names: | sperm acrosome associated 1 |
| NCBI Official Symbol: | SPACA1 |
| NCBI Official Synonym Symbols: | SAMP32 |
| NCBI Protein Information: | sperm acrosome membrane-associated protein 1 |
| UniProt Protein Name: | Sperm acrosome membrane-associated protein 1 |
| UniProt Synonym Protein Names: | Sperm acrosomal membrane-associated protein 32 |
| Protein Family: | Sperm acrosome membrane-associated protein |
| UniProt Gene Name: | SPACA1 |
| UniProt Entry Name: | SACA1_HUMAN |
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