SP2 Transcription Factor Activity Assay
- SKU:
- TFAB00161
- Product Type:
- ELISA Kit
- ELISA Type:
- Transcription Factor Assay
- Analytes:
- SP2
- Reactivity:
- Human
- Reactivity:
- Mouse
Description
system_update_altDatasheet
| Product Name: | SP2 Transcription Factor Activity Assay |
| Product Code: | TFAB00161 |
| Target: | SP2 |
| Reactivity: | Human, Mouse |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie SP2 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | SP2: Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Belongs to the Sp1 C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor; C2H2-type zinc finger protein Chromosomal Location of Human Ortholog: 17q21.32 Cellular Component: nucleus Molecular Function:histone deacetylase binding; protein binding Biological Process: immune response; regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q02086 |
| NCBI GenInfo Identifier: | 119370531 |
| NCBI Gene ID: | 6668 |
| NCBI Accession: | Q02086.3 |
| UniProt Secondary Accession: | Q02086,A6NK74, |
| UniProt Related Accession: | Q02086 |
| Molecular Weight: | 64,153 Da |
| NCBI Full Name: | Transcription factor Sp2 |
| NCBI Synonym Full Names: | Sp2 transcription factor |
| NCBI Official Symbol: | SP2 |
| NCBI Protein Information: | transcription factor Sp2 |
| UniProt Protein Name: | Transcription factor Sp2 |
| Protein Family: | Sex-specific storage-protein |
| UniProt Gene Name: | SP2 |
| UniProt Entry Name: | SP2_HUMAN |
| Antibodies |
| SP2 Antibody (PACO05109) |
