SOX2 Polyclonal Antibody (CAB6171)
- SKU:
- CAB6171
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | SOX2 Polyclonal Antibody |
| Product Code: | CAB6171 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:2000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa |
| Cellular Location: | Nucleus |
| Customer Validation: | WB(Mus musculus, Homo sapiens) |
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human SOX2 (NP_003097.1). |
| Sequence: | MYNMM ETELK PPGPQ QTSGG GGGNS TAAAA GGNQK NSPDR VKRPM NAFMV WSRGQ RRKMA QENPK MHNSE ISKRL GAEWK LLSET EKRPF IDEAK RLRAL HMKEH PDYKY RPRRK TKTLM KKDKY TLPGG LLAPG GNSMA |
| Synonyms: | ANOP3, MCOPS3 |
| Calculated MW: | 34kDa |
| Observed MW: | 36kDa |
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