SOX12 Transcription Factor Activity Assay
- SKU:
- TFAB00199
- Product Type:
- ELISA Kit
- ELISA Type:
- Transcription Factor Assay
- Analytes:
- SOX12
- Reactivity:
- Human
- Reactivity:
- Mouse
Description
| Product Name: | SOX12 Transcription Factor Activity Assay |
| Product Code: | TFAB00199 |
| Target: | SOX12 |
| Reactivity: | Human, Mouse |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie SOX12 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | Function: Binds to the sequence 5'-AACAAT-3' |
| UniProt Protein Details: | By similarity. Subcellular location: Nucleus Ref.1. Tissue specificity: Expressed most abundantly in the CNS. Also expressed in fetal brain and kidney and adult heart, pancreas, testis and ovary. Other tissues were only weakly positive. Ref.1 Sequence similarities: Contains 1 HMG box DNA-binding domain. Sequence caution: The sequence AAB69627.1 differs from that shown. Reason: Frameshift at positions 135 and 201. |
| NCBI Summary: | Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types. [provided by RefSeq, Jan 2013] |
| UniProt Code: | O15370 |
| NCBI GenInfo Identifier: | 21264339 |
| NCBI Gene ID: | 6666 |
| NCBI Accession: | NP_008874 |
| UniProt Related Accession: | O15370 |
| Molecular Weight: | 34kDa |
| NCBI Full Name: | transcription factor SOX-12 |
| NCBI Synonym Full Names: | SRY-box 12 |
| NCBI Official Symbol: | SOX12 |
| NCBI Official Synonym Symbols: | SOX22 |
| NCBI Protein Information: | transcription factor SOX-12 |
| UniProt Protein Name: | Transcription factor SOX-12 |
| UniProt Synonym Protein Names: | Protein SOX-22 |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | SOX12 |
| UniProt Entry Name: | SOX12_HUMAN |
| Antibodies |
| SOX12 Antibody (PACO05107) |
