SOS2 Antibody (PACO22628)
- SKU:
- PACO22628
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SOS2 Antibody (PACO22628) |
| Antibody SKU: | PACO22628 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from internal of human SOS2. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from K562 cells and Jurkat cells, using SOS2 antibody. |
| Background: | Promotes the exchange of Ras-bound GDP by GTP By similarity. |
| Synonyms: | Son of sevenless homolog 2; SOS-2; SOS2; |
| UniProt Protein Function: | SOS2: a guanine nucleotide exchange factor that activates Ras by catalyzing the exchange of bound GDP for GTP. Interacts with GRB2.Protein type: Motility/polarity/chemotaxis; GEFs, Ras; GEFs; Adaptor/scaffoldChromosomal Location of Human Ortholog: 14q21Cellular Component: cytosolMolecular Function: Rho guanyl-nucleotide exchange factor activity; protein binding; DNA binding; protein heterodimerization activityBiological Process: positive regulation of small GTPase mediated signal transduction; axon guidance; regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; positive regulation of apoptosis; small GTPase mediated signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q07890 |
| NCBI GenInfo Identifier: | 154689780 |
| NCBI Gene ID: | 6655 |
| NCBI Accession: | NP_008870.2 |
| UniProt Secondary Accession: | Q07890,Q15503, Q17RN1, D3DSB4 |
| UniProt Related Accession: | Q07890 |
| Molecular Weight: | 152,979 Da |
| NCBI Full Name: | son of sevenless homolog 2 |
| NCBI Synonym Full Names: | son of sevenless homolog 2 (Drosophila) |
| NCBI Official Symbol: | SOS2 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | son of sevenless homolog 2; SOS-2; guanine nucleotide exchange factor; guanine nucleotide releasing factor |
| UniProt Protein Name: | Son of sevenless homolog 2 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Son of sevenless |
| UniProt Gene Name: | SOS2 |
| UniProt Entry Name: | SOS2_HUMAN |
| Antibodies |
| SOS2 Antibody (PACO05105) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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