Sorbitol Dehydrogenase Monoclonal Antibody
- SKU:
- CAB21952
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Sorbitol Dehydrogenase Monoclonal Antibody |
| Product Code: | CAB21952 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC53945 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:2000-1:20000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HT-29, Mouse kidney, Mouse liver, Rat kidney, Rat liver |
| Cellular Location: | Cell projection, Mitochondrion membrane, Peripheral membrane protein, cilium, flagellum |
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Sorbitol Dehydrogenase (NP_003095.2). |
| Sequence: | RENDE FCKMG RYNLS PSIFF CATPP DDGNL CRFYK HNAAF CYKLP DNVTF EEGAL IEPLS VGIHA CRRGG VTLGH KVLVC GAGPI GMVTL LVAKA MGAAQ V |
| Synonyms: | RDH, SDH, XDH, SORD1, SORDD, HEL-S-95n |
| Calculated MW: | 38kDa |
| Observed MW: | 38kDa |
Related Products
Sorbitol Dehydrogenase Polyclonal Antibody
OverviewProduct Name:Sorbitol Dehydrogenase Polyclonal AntibodyProduct Code:CAB22009Reactivity:Human, Mouse, RatApplications:West
Sorbitol Dehydrogenase Polyclonal Antibody,glycerol and sodium azide free
Sorbitol Dehydrogenase Polyclonal Antibody,glycerol and sodium azide freeThe product page for this antibody is being prepared. If you have a question please don't hesitate to get in touch!
