SOD1 Monoclonal Antibody (CAB21211)
- SKU:
- CAB21211
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IHC
Description
| Product Name: | SOD1 Monoclonal Antibody |
| Product Code: | CAB21211 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC51786 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | IHC-P, ELISA |
| Key Applications: | Immunohistochemistry |
| Recommended Dilution: | IHC-P 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasm, Nucleus |
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2-154 of human SOD1 (NP_000445.1). |
| Sequence: | ATKAV CVLKG DGPVQ GIINF EQKES NGPVK VWGSI KGLTE GLHGF HVHEF GDNTA GCTSA GPHFN PLSRK HGGPK DEERH VGDLG NVTAD KDGVA DVSIE DSVIS LSGDH CIIGR TLVVH EKADD LGKGG NEEST KTGNA GSRLA CGVIG IAQ |
| Synonyms: | ALS, SOD, ALS1, IPOA, STAHP, hSod1, HEL-S-44, homodimer |
| Calculated MW: | 16kDa |
| Observed MW: | Refer to figures |
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