SNX27 Antibody (PACO17132)
- SKU:
- PACO17132
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SNX27 Antibody (PACO17132) |
| Antibody SKU: | PACO17132 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:10-1:50 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Fusion protein of human SNX27 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO17132(SNX27 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17132(SNX27 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | This gene encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein. |
| Synonyms: | sorting nexin family member 27 |
| UniProt Protein Function: | SNX27: Involved in endocytic trafficking. In T lymphocytes, participates in endocytic recycling pathway. Recruits PSCDBP and HT4R to early endosomes. Belongs to the sorting nexin family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 1q21.3 Cellular Component: cytoplasm; early endosome; immunological synapse; nucleoplasm; retromer complex Molecular Function:phosphatidylinositol 3-phosphate binding; protein binding Biological Process: endosome transport; establishment of natural killer cell polarity; intracellular protein transport |
| NCBI Summary: | This gene encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96L92 |
| NCBI GenInfo Identifier: | 166214988 |
| NCBI Gene ID: | 81609 |
| NCBI Accession: | Q96L92.2 |
| UniProt Secondary Accession: | Q96L92,Q32Q36, Q4AEJ5, Q5VWB0, Q5VWB1, Q5VWB2, Q6IPP6 Q86UB1, Q96D79, Q9H3K8, |
| UniProt Related Accession: | Q96L92 |
| Molecular Weight: | 27,781 Da |
| NCBI Full Name: | Sorting nexin-27 |
| NCBI Synonym Full Names: | sorting nexin family member 27 |
| NCBI Official Symbol: | SNX27 |
| NCBI Official Synonym Symbols: | MRT1; MY014 |
| NCBI Protein Information: | sorting nexin-27 |
| UniProt Protein Name: | Sorting nexin-27 |
| Protein Family: | Sorting nexin |
| UniProt Gene Name: | SNX27 |
| UniProt Entry Name: | SNX27_HUMAN |
| Antibodies |
| SNX27 Antibody (PACO12382) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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