Description
Antibody Name: | SNX27 Antibody (PACO12382) |
Antibody SKU: | PACO12382 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human SNX27 |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | sorting nexin family member 27;SNX27;KIAA0488;MGC126871;MGC126873;MGC20471;MRT1;MY014 ; |
UniProt Protein Function: | SNX27: Involved in endocytic trafficking. In T lymphocytes, participates in endocytic recycling pathway. Recruits PSCDBP and HT4R to early endosomes. Belongs to the sorting nexin family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 1q21.3 Cellular Component: cytoplasm; early endosome; immunological synapse; nucleoplasm; retromer complex Molecular Function:phosphatidylinositol 3-phosphate binding; protein binding Biological Process: endosome transport; establishment of natural killer cell polarity; intracellular protein transport |
NCBI Summary: | This gene encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q96L92 |
NCBI GenInfo Identifier: | 166214988 |
NCBI Gene ID: | 81609 |
NCBI Accession: | Q96L92.2 |
UniProt Secondary Accession: | Q96L92,Q32Q36, Q4AEJ5, Q5VWB0, Q5VWB1, Q5VWB2, Q6IPP6 Q86UB1, Q96D79, Q9H3K8, |
UniProt Related Accession: | Q96L92 |
Molecular Weight: | 27,781 Da |
NCBI Full Name: | Sorting nexin-27 |
NCBI Synonym Full Names: | sorting nexin family member 27 |
NCBI Official Symbol: | SNX27 |
NCBI Official Synonym Symbols: | MRT1; MY014 |
NCBI Protein Information: | sorting nexin-27 |
UniProt Protein Name: | Sorting nexin-27 |
Protein Family: | Sorting nexin |
UniProt Gene Name: | SNX27 |
UniProt Entry Name: | SNX27_HUMAN |