Description
| Product Name: | Snail Monoclonal Antibody |
| Product Code: | CAB24806 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunofluorescence, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62698 |
| Reactivity: | Human |
| Tested Applications: | WB, IF/ICC, IP, ELISA |
| Key Applications: | Western blotting, Immunofluorescence, Immunoprecipitation |
| Recommended Dilution: | WB 1:2000-1:10000, IF/ICC 1:50-1:200, IP 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T transfected with Snail (Human) |
| Cellular Location: | Cytoplasm, Nucleus |
The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-157 of human Snail (NP_005976.2). |
| Sequence: | QESPR VAELT SLSDE DSGKG SQPPS PPSPA PSSFS STSVS SLEAE AYAAF PGLGQ VPKQL AQLSE AKDLQ ARKAF NCK |
| Synonyms: | SNA, SNAH, SNAIL, SLUGH2, SNAIL1, dJ710H13.1 |
| Calculated MW: | 29kDa |
| Observed MW: | 35kDa |
