SMPD1 Monoclonal Antibody
- SKU:
- CAB23894
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | SMPD1 Monoclonal Antibody |
| Product Code: | CAB23894 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62108 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:1000-1:3000, IHC-P 1:50, -1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | SK-MEL-28, HeLa, rat liver |
| Cellular Location: | Lysosome |
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-340 of human SMPD1(NP_000534.3). |
| Sequence: | PARLH RIVPR LRDVF GWGNL TCPIC KGLFT AINLG LKKEP NVARV GSVAI KLCNL LKIAP PAVCQ SIVHL FEDDM VEVWR RSVLS PSEAC GLLLG STCGH WDIFS SWNIS LPTVP KPPPK PPSPP APGAP VSRIL FLTDL HWDHD YLEGT DPDCA DPLCC RRGSG LPPAS RPGAG YWGEY SKCDL PLRTL ESLLS GLGPA GPFDM VYWTG DIPAH DVWHQ TRQDQ LRALT TVTAL VRKFL GPVPV YPAVG NHEST PVNSF PPPFI EGNHS S |
| Synonyms: | ASM, NPD, ASMASE |
| Calculated MW: | 70kDa |
| Observed MW: | 57kDa/70kDa |
Related Products
IκBα Monoclonal Antibody
OverviewProduct Name:IκBα Monoclonal AntibodyProduct Code:CAB24909Reactivity:Human, Mouse, RatApplications:Western blotting, Immu
Chk1 Monoclonal Antibody
OverviewProduct Name:Chk1 Monoclonal AntibodyProduct Code:CAB22055Reactivity:HumanApplications:Western blotting
HN1 Monoclonal Antibody
OverviewProduct Name:HN1 Monoclonal AntibodyProduct Code:CAB23553Reactivity:Human, MouseApplications:Western blotting
RAB5A Monoclonal Antibody
OverviewProduct Name:RAB5A Monoclonal AntibodyProduct Code:CAB23955Reactivity:Human, Mouse, RatApplications:Western blotting, Imm
Palladin Monoclonal Antibody
OverviewProduct Name:Palladin Monoclonal AntibodyProduct Code:CAB23566Reactivity:HumanApplications:Western blotting
ATP6V0C Monoclonal Antibody
OverviewProduct Name:ATP6V0C Monoclonal AntibodyProduct Code:CAB23757Reactivity:HumanApplications:Western blotting<
BCL2L15 Monoclonal Antibody
OverviewProduct Name:BCL2L15 Monoclonal AntibodyProduct Code:CAB23570Reactivity:HumanApplications:Western blotting<