Description
| Product Name: | SMG1 Rabbit pAb |
| Product Code: | CAB21169 |
| Application: | IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SMG1 (NP_055907.3). |
| Applications: | IF |
| Recommended Dilution: | IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SMG1 (NP_055907.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSRR APGS RLSS GGGG GGTK YPRS WNDW QPRT DSAS ADPD NLKY SSSR DRGG SSSY GLQP SNSA VVSR QRHD DTRV HADI QNDE KGGY SVNG GSGE NTYG |
| Gene ID: | 23049 |
| Cellular Location: | |
| Calculated MW: | 410kDa |
| Observed MW: | Refer to figures |
| Synonyms: | ATX, LIP, 61E3.4 |
| Uniprot: | Q96Q15 |
| Background: | This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternatively spliced transcript variants have been described, but their full-length nature has yet to be determined. |