SMAGP Antibody (PACO20549)
- SKU:
- PACO20549
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SMAGP Antibody (PACO20549) |
| Antibody SKU: | PACO20549 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide of human SMAGP |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20549(SMAGP Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20549(SMAGP Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | SMAGP (small transmembrane and glycosylated protein) is a 97 amino acid, single-pass type III membrane protein that localizes to the membrane of cytoplasmic vesicles. Existing as a murine-specific protein, SMAGP is thought to play a role in epithelial cell-cell contacts and, via its ability to control cell adhesion, may be involved in tumor formation, as well as overall tumor invasiveness and metastasis. SMAGP is subject to post-translational O-glycosylation which is thought to be modified with sialic acid, residues. The gene encoding SMAGP maps to murine chromosome 15. |
| Synonyms: | small cell adhesion glycoprotein |
| UniProt Protein Function: | SMAGP: May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation. Belongs to the SMAGP family.Protein type: Vesicle; Membrane protein, integralChromosomal Location of Human Ortholog: 12q13.13Cellular Component: nucleoplasm; cytoplasmic vesicle membrane; plasma membrane; integral to membrane; cell junction |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q0VAQ4 |
| NCBI GenInfo Identifier: | 76496485 |
| NCBI Gene ID: | 57228 |
| NCBI Accession: | NP_001026798.1 |
| UniProt Secondary Accession: | Q0VAQ4,A6NIL5 |
| UniProt Related Accession: | Q0VAQ4 |
| Molecular Weight: | 10679 |
| NCBI Full Name: | small cell adhesion glycoprotein |
| NCBI Synonym Full Names: | small cell adhesion glycoprotein |
| NCBI Official Symbol: | SMAGP |
| NCBI Official Synonym Symbols: | hSMAGP |
| NCBI Protein Information: | small cell adhesion glycoprotein |
| UniProt Protein Name: | Small cell adhesion glycoprotein |
| UniProt Synonym Protein Names: | Small transmembrane and glycosylated protein |
| Protein Family: | Small cell adhesion glycoprotein |
| UniProt Gene Name: | SMAGP |
| UniProt Entry Name: | SMAGP_HUMAN |
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