Description
Antibody Name: | SMAGP Antibody (PACO20548) |
Antibody SKU: | PACO20548 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human SMAGP |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO20548(SMAGP Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20548(SMAGP Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | SMAGP (small transmembrane and glycosylated protein) is a 97 amino acid, single-pass type III membrane protein that localizes to the membrane of cytoplasmic vesicles. Existing as a murine-specific protein, SMAGP is thought to play a role in epithelial cell-cell contacts and, via its ability to control cell adhesion, may be involved in tumor formation, as well as overall tumor invasiveness and metastasis. SMAGP is subject to post-translational O-glycosylation which is thought to be modified with sialic acid, residues. The gene encoding SMAGP maps to murine chromosome 15. |
Synonyms: | small cell adhesion glycoprotein |
UniProt Protein Function: | SMAGP: May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation. Belongs to the SMAGP family.Protein type: Vesicle; Membrane protein, integralChromosomal Location of Human Ortholog: 12q13.13Cellular Component: nucleoplasm; cytoplasmic vesicle membrane; plasma membrane; integral to membrane; cell junction |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q0VAQ4 |
NCBI GenInfo Identifier: | 76496485 |
NCBI Gene ID: | 57228 |
NCBI Accession: | NP_001026798.1 |
UniProt Secondary Accession: | Q0VAQ4,A6NIL5 |
UniProt Related Accession: | Q0VAQ4 |
Molecular Weight: | 10679 |
NCBI Full Name: | small cell adhesion glycoprotein |
NCBI Synonym Full Names: | small cell adhesion glycoprotein |
NCBI Official Symbol: | SMAGP |
NCBI Official Synonym Symbols: | hSMAGP |
NCBI Protein Information: | small cell adhesion glycoprotein |
UniProt Protein Name: | Small cell adhesion glycoprotein |
UniProt Synonym Protein Names: | Small transmembrane and glycosylated protein |
Protein Family: | Small cell adhesion glycoprotein |
UniProt Gene Name: | SMAGP |
UniProt Entry Name: | SMAGP_HUMAN |